L-Methylfolate is the only form of folate that crosses the blood-brain barrier and goes straight to work. It powers over 200 processes the body relies on for healthy development. It activates the enzymes the brain uses to produce dopamine, serotonin, and norepinephrine, the chemicals that govern mood, focus, language, and sensory processing. When L-Methylfolate is present, the methylation cycle starts spinning again. Glutathione rebuilds. The brain finally gets the fuel it's been missing.