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Neupril Pure Methylfolate

Neupril Pure Methylfolate

The delicious, bioavailable form of methylfolate for your daily boost of focus, mood, and energy.

task_alt Supports methylation & brain health

task_alt Clears brain fog & reduces fatigue

task_alt Boosts focus, clarity, & sustained energy

task_alt Promotes healthy stress response

task_alt Helps regulate homocysteine levels

All natural, safe & made in USA

30-Day Money Back Guarantee

Neupril Pure Methylfolate

Neupril Pure Methylfolate

 (1,305 Reviews)
Regular price $44.99
Regular price $44.99 Sale price
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Why Neupril?

It’s Simple!

Neupril Pure Methylfolate gives you the active form of folate your body can readily use. This is especially important if you have an MTHFR gene variant.

Comprehensive: L-Methylfolate is the bioactive form of folate, supporting mood, focus, energy, and overall neurological health, without the conversion issues linked to MTHFR.

Delicious: A smooth berry liquid that makes daily nutrition an easy habit you’ll want to keep.

Portable: Designed to fit your lifestyle, whether at work, home, or on the go. Just measure and take.

No Mess, No Stress: Forget the pills and chalky powders. One liquid solution for simple, effective nutrition.

Ingredients & Allergies

Neupril Pure Methylfolate are crafted with high-quality, active ingredients to support your neurological health:

• L-Methylfolate (15 mg): The bioactive form of folate, crucial for neurotransmitter synthesis and methylation processes.

• Methylcobalamin (Vitamin B12): An active form of B12 that supports nerve health and cognitive function.

• Organic Berry Flavor: Natural flavors for a pleasant taste experience.

• Purified Water: Serves as the base for the liquid formulation.

• Glycerin: A plant-based sweetener and stabilizer.

• Citric Acid: Maintains the product's stability and pH balance.

• Potassium Sorbate: A preservative to ensure product freshness.

Allergies
Neupril Pure Methylfolate is non-GMO, vegetarian, and made for everyday wellness. This liquid is free from gluten, dairy, soy, nuts, and artificial additives. No synthetic sweeteners, no synthetic dyes.

Science & Certifications

Clinically Tested
Neupril is built on science, formulated with bioavailable L-Methylfolate and Methyl B12, ingredients supported by decades of clinical research. Our formula is designed for real absorption and impact, helping your body and brain get what they need to function clearly and feel balanced. It’s not just about convenience, it’s about effectiveness you can feel.

Third Party Testing
Every batch of Neupril undergoes third-party testing to ensure safety, potency, and label accuracy. We test for heavy metals, microbial contaminants, and ingredient integrity so you can feel confident about what you’re putting in your body. Clean, effective, and transparent as always.

Certifications
Neupril is manufactured in NSF, GMP-certified, and FDA-registered facilities in the United States. We prioritize high standards at every step, from sourcing to bottling, to ensure consistent quality you can trust.

Shipping & Returns

Shipping: At Neupril, we pride ourselves on fast and efficient service. Orders are processed within 24-48 hours (excluding weekends/holidays) and typically arrive within 3-7 business days.

Returns: We offer a flexible 30-day return policy for your satisfaction. If you’re not happy with your purchase, return or exchange it within 30 days.

Directions

1. Shake Well: Ensure the bottle is well-shaken before each use to mix the ingredients thoroughly.

2. Apply 10 Drops: Take your dropper and add 10 drops (.5ml) under your tongue for enhanced absorption.

3. Experience The Benefits: Sit tight and wait for a new sense of clarity to kick in!

Benefits

The benefits of Neupril Pure Methylfolate could fill a whole list. Try saying all of this in one breath: improved mood, sharper focus, relief from fatigue, support for MTHFR, and mood, balanced neurotransmitter function, addiction recovery support, better sleep, steady energy, cognitive clarity, stress resilience, and overall brain and body wellness.

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VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

VEGAN

BIOAVAILABLE FORM

THIRD-PARTY TESTED (FOR HEAVY METALS & MIRCOBES)

NON-GMO

NO ARTIFICIAL FILLERS

Week 1

Lift the fog, feel the difference

Methylfolate starts restoring neurotransmitter balance, helping clear brain fog and calm anxious thoughts.*

Month 1

Real energy, not caffeine highs

Steady methylation support helps boost dopamine and serotonin for more focus, drive, and a balanced mood. Without the crash.*

Month 3

Break the burnout cycle

Consistent use supports nervous system recovery and resilience, helping you stay clear-headed, motivated, and grounded even under stress or during recovery.*

Month 6

Rebuild focus and emotional balance

Long-term use strengthens attention, mood stability, and motivation. Helping you feel more like yourself again.*

Clinically Backed Nutrients For Real, Noticeable Benefits

L-5-methyltetrahydrofolate (L-5-MTHF)

KEY FUNCTION

Supports neurotransmitter production

Methylcobalamin (Vitamin B12)

KEY FUNCTION

Essential for red blood cell formation and energy production

L-5-methyltetrahydrofolate (L-5-MTHF)

Supports neurotransmitter production

WHAT IS IT?

Methylfolate is the bioactive form of folate that directly supports neurotransmitter production, DNA synthesis, and healthy cell growth. It bypasses the conversion step many people struggle with due to MTHFR gene variants, ensuring efficient dopamine and serotonin synthesis for balanced mood, focus, and cognitive performance. It also helps regulate homocysteine, reducing oxidative stress and supporting long-term brain and cardiovascular health.

NEUPRIL DOSAGE

15mg

THE SCIENCE

Research shows that 15 mg of L-methylfolate supports cognitive, mood and cellular health by supplying the active form of folate needed for neurotransmitter production, methylation and homocysteine regulation. In fact, studies show doses of 15 mg / day help improve serotonin, dopamine and norepinephrine synthesis and may benefit those with MTHFR-related conversion challenges.

Methylcobalamin (Vitamin B12)

Essential for red blood cell formation and energy production

WHAT IS IT?

Vitamin B12 is an essential nutrient that fuels energy production, supports neurotransmitter balance, and promotes cognitive performance. It’s crucial for dopamine and serotonin synthesis, which drive motivation, mood, and mental clarity, while also aiding red blood cell formation and mitochondrial function. Additionally, B12 helps regulate homocysteine, reducing oxidative stress and supporting long-term brain health.

NEUPRIL DOSAGE

1000mcg

OTHER BRANDS

0.3-4000mcg on average

THE SCIENCE

Research suggests that sufficient B12 supports focus, mental endurance, and cognitive clarity, making it an essential nutrient for sustained energy, motivation, and optimal performance.

Drop it Daily, Feel it Fully

We know Neupril is clean and easy to use, but we wanted to see what happens with consistency. Here’s what thousands of customers reported after 3 months of Neupril.

93%

Of users take Neupril at least 3-5x per week, with 79% taking it every single day.*

84%

Report better mood stability, less irritability, and improved emotional balance.*

67%

Feel more energized throughout the day, and less burntout.*

78%

Say their overall health and well-being have improved since taking Neupril.*

Benefits You Can See and Feel

Energy

Delivers clean, crash-free energy through optimal folate metabolism.

Sleep

Supports restful sleep by balancing key sleep-related neurotransmitters.

Mood

Promotes emotional balance by supporting healthy dopamine levels.

MTHFR

Supports MTHFR function for proper folate metabolism and balance

Focus

Supports clear thinking and sharper concentration with active folate.

Cognition

Backed by science to support memory, clarity, and performance.

Energy

Delivers clean, crash-free energy through optimal folate metabolism.

Sleep

Supports restful sleep by balancing key sleep-related neurotransmitters.

Mood

Promotes emotional balance by supporting healthy dopamine levels.

MTHFR

Supports MTHFR function for proper folate metabolism and balance

Focus

Supports clear thinking and sharper concentration with active folate.

Cognition

Backed by science to support memory, clarity, and performance.

Us vs. Them

No gimmicks. No markups. Just effective, science-backed nutrition that actually fits into your life.

Active Formula

Fast Absorption

Clean Ingredients

3rd Party Tested

Delicious Taste

Neupril

Others

Tested, Trusted, and Certified

Neupril’s active folate is third-party tested to confirm purity, potency, and safety, ensuring every drop meets clinical standards and is free from heavy metals, microbes, and unwanted fillers.

Gluten Free

USA Made

Clinical Studies

Quality Verified

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Trusted by Over 100,000+ Satisfied Customers

Join Others Filling Their Methylation Gaps

THE BEST form of the folic acid you can get and I love this brand! Worth its money and actually helped me a lot!

Chris G.

Love this brand and the effectiveness of this Methylfolate! It helps my energy, hormones, and even sleep quality. It absorbs better and faster than other brands I've had, and it tastes good!

Kylie L.

Love these supplements! Have been taking these pre pregnancy and now that I’m pregnant. I have the MTFHR gene mutation and love that these are methylated.

Lauren B.

Great product. Good quality and very effective. My 73 year old Mother and my family takes it daily. Perfect if you have a MTHFR snippet in your DNA.

Polina Y.

I felt less stressed right away. I did that cheek swab test (from my doctor & sent it in) & it showed that I had one mutation, not two, but, I see a huge difference in my anxiety levels & it's only been a week!

Matthew M.

I love this supplement! I've been taking it for the last couple weeks and have started to feel a difference in my energy levels. It's very easy to take since it's just drops. The price is very affordable for such a high quality product.

Gwen C.

    Any Last Questions?

    Try Neupril

    How quickly will I notice results?

    Most customers report improved focus, energy, and mood within the first few days of consistent use, with more noticeable benefits appearing after 2-4 weeks.

    Are these safe for daily use?

    Yes, Neupril Pure Methylfolate are crafted with natural, high-quality ingredients that are safe for everyday use without harsh side effects. Consult your healthcare provider if you have any specific medical concerns.

    Can I take methylfolate with other supplements or medications?

    Generally, yes. But it’s best to talk to your healthcare provider if you're other medications or supplements.

    Does body weight affect how many drops I should take?

    Not necessarily. Dosage isn’t determined by weight. it’s determined by your body’s methylation needs. Everyone processes folate differently depending on factors like genetics (such as MTHFR variants), stress levels, diet, and overall methylation efficiency. A heavier person doesn’t automatically need more drops. The recommended 10-drop dose is designed to support optimal methylation for most adults. If needed, adjustments should be made based on how you feel or under the guidance of a healthcare professional.

    What if I don't know if I have MTHFR?

    Even without the MTHFR mutation, methylfolate is still the superior form of folate. Instead of relying on conversion steps, Neupril provides the body with the active form of folate it can use immediately enhancing focus, improving mood, and boosting natural energy.

    What does Neupril taste like?

    At Neupril, our drops have a refreshing organic berry flavor that’s light, smooth, and easy to take. Whether under the tongue or mixed into a drink, most people find it pleasantly subtle. Not too sweet, not too strong. Just clean, natural berry goodness you’ll actually enjoy taking every day.